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Due to these properties of prednisone in dogs, the drug is highly effective at treating conditions such as: Allergic reactions As a severe prednisone dependent asthmatic, I am all too familiar with the roller coaster that comes with prednisone tapering. Due to these properties of prednisone in dogs, the drug is highly effective at treating conditions such as: Allergic reactions Asthma Hives and itching. This makes prednisone an effective treatment option for autoimmune diseases, which are caused by an overactive immune system attacking different organs in the body. There’s a little bit of evidence that omega-3 supplements may provide some relief for dogs suffering from skin inflammation, but more research is needed Prednisone is a corticosteroid that is used often as an immunosuppressant drug in the treatment of a number of dog illnesses. ” It includes prednisone, methylprednisolone, dexamethasone and several brand-name medications like Temaril-P. 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